研究成果 | 科研项目 1. 国家自然科学基金委员会, 地区基金项目, 32160808, 海南砂仁多糖影响仔猪小肠绒毛形态的作用与机制研究, 202201~202512, 35万元, 在研. 2. 国家自然科学基金委员会, 青年基金项目, 31802234, 益智仁多糖抗猪流行性腹泻病毒的作用与机制研究, 201901~202112, 26万元, 结题. 3. 海南省科技厅, 重点研发计划, ZDYF2022XDNY141, 海南砂仁多糖-镁调控文昌鸡生长性能的关键技术研究, 202203~202403, 30万元, 结题. 4. 海南省科技厅, 重点研发计划, ZDYF2019085, 鸡传染性法氏囊病VP2亚单位疫苗的南药多糖PLGA免疫佐剂研究, 201904~202104, 32万元, 结题. 5. 海南省科技厅, 青年基金项目, 318QN202, 基于淋巴细胞和巨噬细胞的益智仁多糖增强免疫活性研究, 201803~201912, 5万元, 结题. 学术论文： 1. Yun Chen*, Qiyuan Luo, Haowen Wu, Quanjiang Wang, Yue Zhang. Amomum longiligulare polysaccharide 1 supplementation promotes the proliferation of jejunal epithelial cells in piglets by regulating jejunal metabolites [J]. International Journal of Biological Macromolecules, 2025, 306, 141366. 2. Qiyuan Luo, Quanjiang Wang, Haowen Wu, Yun Chen*. Areca nut polysaccharide induces M1 macrophage polarization through the NF-κB and MAPK pathways independent of TLR2 and TLR4 signaling [J]. International Journal of Biological Macromolecules, 2024, 281, 136379. 3. Haowen Wu, Huricha Chen, Jiaguo Liu, Zengyang Xing, Jiahao Ni, Ling Teng,Yun Chen*. Amomum longiligulare polysaccharide 1- PLGA nanoparticle promotes the immune activities of T lymphocytes and dendritic cells [J]. International Immunopharmacology, 2022 112, 109204. 4. Jiahao Ni, Huricha Chen, Chenglong Zhang, Qiyuan Luo, Yao Qin, Yuhui Yang,Yun Chen*. Characterization of Alpinia officinarum Hance polysaccharide and its immune modulatory activity in mice [J]. Food & Function, 2022, 13, 2228-2237. 5. Yongjian Zhu, Xiru Wang, Chenglong Zhang, Jiahao Ni, Qiyuan Luo, Ling Teng, Suya Liao, Yuhui Yang, Huricha Chen,Yun Chen*. Characterizations of glucose-rich polysaccharides from Amomum longiligulare T.L.Wu fruits and their effects on immunogenicities of infectious bursal disease virus VP2 protein [J]. International Journal of Biological Macromolecules, 2021, 183, 1574-1584.
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