研究成果 | 科研项目: 1. 海南省地方鸡产业体系，儋州鸡资源育种岗，202401-202612，参与，在研。 2. 海南省科技厅，海南省自然科学基金高层次人才项目：322RC572，豆蔻明对缓解慢性热应激儋州鸡肠粘膜屏障损伤的机制研究，202205-202512，主持，结题。 3. 国家自然科学基金委员会，地区科学基金项目：32060757，基于AhR/Nrf2/NQO1信号通路对缓解断奶仔猪肠道炎症的机制研究及豆蔻明的调控，202101-202412，主持，结题。 4. 国家自然科学基金委员会，青年科学基金项目：31301990，姜黄素对断奶仔猪肠粘膜屏障的保护作用及其机制研究，研究期限：201401-201612，主持，结题。 5. 海南省科协，青年科技英才学术创新计划项目：QCXM201907，大黄素对断奶仔猪肠粘膜屏障损伤的修复机理研究，研究期限：201909-202112，主持，结题。 6. 海南省科技厅，海南省自然科学基金：20153079，不同断奶日龄仔猪肠粘膜屏障变化规律研究，2015.01-2016.12，主持，已结题。 学术论文: (1) An ZX, Shi LG, Hou GY, Xun WJ*, Genetic diversity and selection signatures in Hainan black goats revealed by whole-genome sequencing data[J]. Animal, 2024, 18:101147.（中科院1区top期刊） (2) Jiang HR, Shi LG, Deng TJ, Hou GY, Xun WJ*, Effects of cardamonin on the growth performance, intestinal barrier function and intestinal microbiota of Danzhou chickens under heat stress[J]. Poultry Science, 2024, 103:104362. (3) An ZX, Shi LG, Zhou HL, Hou GY, Xun WJ*. Exploratory metabolomics and lipidomics profiling contributes to understanding how curcumin improves quality of goat semen stored at 16 °C in tropical areas[J].Int J Mol Sci, 2024, 25(18):10200. (4) Wu XM, Zhang YL, Ji MY, Yang W, Deng TJ, Hou GY, Shi LG, Xun WJ*. AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism[J]. Animals, 2024, 14(5): 794. (5) Xun WJ#*, Ji MY#, Ma ZH, Deng TJ, Yang W, Hou GY, Shi LG, Cao T, Dietary emodin alleviates lipopolysaccharide-induced intestinal mucosal barrier injury by regulating gut microbiota in piglets[J]. Animal Nutrition, 2023, 14:152-162. （中科院1区top期刊） (6) Xun WJ#*, Fu QY#, Shi LG, Cao T, Jiang HZ, Ma ZH. Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat[J]. International Immunopharmacology, 2021 99:107989. (7) Fu QY, Tan Z, Shi LG, Xun WJ*. Resveratrol Attenuates diquat-induced oxidative stress by regulating gut microbiota and metabolome characteristics in piglet [J]. Froniters in Microbiology, 2021: 12: 695155. (8) Xun WJ, Fu QY, Hou GY, Shi LG, Cao T. Protective effects of dietary resveratrol supplementation against oxidative stress in diquat-challenged piglets [J]. Italian Journal of Animal Science, 2020, 19(1):1523-1532. (9) Shi LG, Zhang Y, Wu LL, Xun WJ*, Liu Q*, Cao T, Hou GY, Zhou HL. Moderate coconut oil supplement ameliorates growth performance and ruminal fermentation in Hainan black goat kids[J]. Frontiers in Veterinary Science, 2020, 7:622259. (10) Shi LG, Xun WJ, Peng W, Hu H, Cao T, Hou G. Effect of the single and combined use of curcumin and piperine on growth performance, intestinal barrier function, and antioxidant capacity of weaned Wuzhishan piglets[J]. Frontiers in Veterinary Science, 2020, 7: 418. (11) Xun WJ, Shi LG, Zhou HL, Hou GY, Cao T. Effect of weaning age on intestinal mucosal morphology, permeability, gene expression of tight junction proteins, cytokines and secretory IgA in Wuzhishan mini piglets[J]. Italian Journal of Animal Science, 2018, 17(4):976-983. (12) Xun WJ, Shi LG, Zhou HL, Hou GY, Cao T, Zhao P. Effects of curcumin on growth performance, jejunal mucosal membrane integrity, morphology and immune status in weaned piglets challenged with enterotoxigenic Escherichia coli[J]. International Immunopharmacology, 2015,27:46-52. 发明专利： 一种用于缓解高温应激的山羊精液稀释液、制备及其应用方法，2021-07-27，中国，ZL201710379447.8，第2完成人。 著作教材: （1）《牛场消毒防疫与疾病防制》，河南科学技术出版社，2018，独立主编。 （2）《高效健康养猪关键技术》，中国农业科学技术出版社，2020，第一主编（合著），本人编写10万字。 地方标准： 近交系五指山猪生产操作技术规程，DB469003/T11-2018，海南省儋州质量技术监督局发布。 |
